产品货号:
Z18162
中文名称:
HTR1A抗体
英文名称:
Anti-HTR1A Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-HTR1A Antibody |
指标别名 | 5 HT 1A;5 HT1A;5HT1a;ADRB2RL1;ADRBRL1;G 21;HTR1A;Serotonin receptor 1A |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC,IF,ELISA |
基因名称 | HTR1A |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from human SR-1A |
计算分子量 | 46KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | HTR1A(5-HYDROXYTRYPTAMINE RECEPTOR 1A),also called SEROTONIN 5-HT-1A RECEPTOR or BETA-2-ADRENERGIC RECEPTOR-LIKE PROTEIN G-21,is a subtype of 5-HT receptor that binds the endogenous neurotransmitter serotonin.It is a G protein-coupled receptor(GPCR) that is coupled to Gi/Go and mediates inhibitory neurotransmission.HTR1A denotes the human gene encoding for the receptor.The HTR1A gene is located at 5q12.3.The decreases in 5-HT-1A receptor densities correlated with decreased glucose utilization as measured by PET scan.Activation of 5-HT-1A receptors has been demonstrated to impair cognition,learning,and memory by inhibiting the release of glutamate and acetylcholine in various areas of the brain.5-HT-1A receptors in the dorsal raphe nucleus are co-localized with neurokinin 1(NK1) receptors and have been shown to inhibit the release of substance P,their endogenous ligand. |
Uniprot ID | P08908 |
基因名全称 | 5-hydroxytryptamine receptor 1A |
蛋白名全称 | 5-hydroxytryptamine receptor 1A |
推荐稀释比 | WB 1:500~1:2000 IHC 1:100~1:300 IF 1:200~1:1000 ELISA 1:20000 |
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